Czasopismo | PRZEMYSŁ SPOŻYWCZY | Rocznik 2024 - zeszyt 6

Walory prozdrowotne kwasów omega-3

Health-promoting benefits of omega-3 fatty acids

10.15199/65.2024.6.6

nr katalogowy: 149069
10.15199/65.2024.6.6

Streszczenie

Kwasy tłuszczowe omega-3 to niezbędne dla zdrowia wielonienasycone kwasy tłuszczowe, które organizm musi pozyskiwać zpożywienia. Najważniejsze znich to kwas alfa-linolenowy (ALA), kwas eikozapentaenowy (EPA) ikwas dokozaheksaenowy (DHA). ALA znajduje się głównie w roślinach, natomiast EPA i DHA w rybach morskich ioleju zalg. Regularne spożywanie omega-3 zapewnia liczne korzyści zdrowotne, w tym m.in. ochronę układu sercowo-naczyniowego, poprawęstanu wątroby, złagodzenie objawów zapalenia stawów, wsparcie dla kobiet zPCOS, jakrównież znajduje zastosowanie w przypadku cukrzycy typu2, depresji, łuszczycy, migreny czy astmy. Zalecane dzienne spożycie omega-3 to ok. 500 mg, przy czym większe dawki mogą być wymagane dla skutecznego wspomagania leczenia różnych schorzeń

Abstract

Omega-3 fatty acids are essential polyunsaturated fatty acids for health, which the body must obtain from food. The most important of these are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA) anddocosahexaenoic acid (DHA). ALA is mainly found in plants, while EPA and DHA are found in marine fish and algae oil. Regular consumption of omega-3 provides numerous health benefits, including cardiovascular protection, improved liver health, relief of arthritis symptoms, support for women with PCOS, as well as being used for type2 diabetes, depression, psoriasis, migraine or asthma, among others. The recommended daily intake of omega-3 is about 500 mg, with higher doses may be required to support treatment of various conditions.

Słowa kluczowe

Keywords

Bibliografia

[1] Abreu A.M., C.L.K. Copetti, D.B. Hauschild, P.F. Di Pietro & E. Wazlawik. 2022. Effects of supplementation with vegetable sources of alpha-linolenic acid (ALA) on inflammatory markers and lipid profile in individuals with chronic kidney disease: A systematic review and meta-analysis. Clinical nutrition (Edinburgh, Scotland), 41(6), 1434-1444. https://doi.org/10.1016/j.clnu.2022.02.013
[2] Adams S., A.L. Lopata, C.M. Smuts, R. Baatjies & M.F. Jeebhay. 2018. Relationship between Serum Omega-3 Fatty Acid and Asthma Endpoints. International journal of environmental research and public health, 16(1), 43. https://doi.org/10.3390/ijerph16010043
[3] Ajabnoor S. M., G. Thorpe, A. Abdelhamid & L. Hooper. 2021. Long-term effects of increasing omega-3, omega-6 and total polyunsaturated fats on inflammatory bowel disease and markers of inflammation: a systematic review and meta-analysis of randomized controlled trials. European journal of nutrition, 60(5), 2293-2316. https://doi.org/10.1007/s00394-020-02413-y
[4] Begtrup K. M., A.E. Krag & A.M. Hvas. 2017. No impact of fish oil supplements on bleeding risk: a systematic review. Danish medical journal, 64(5), A5366.
[5] Behboudi-Gandevani S., F.Z. Hariri & L. Moghaddam-Banaem. 2018. The effect of omega 3 fatty acid supplementation on premenstrual syndrome and health-related quality of life: a randomized clinical trial. Journal of psychosomatic obstetrics and gynaecology, 39(4), 266-272. https://doi.org/10.1080/01 67482X.2017.1348496
[6] Brigham E. P., H. Woo, M. McCormack, J. Rice, K. Koehler, T. Vulcain, T. Wu, A. Koch, S. Sharma, F. Kolahdooz, S. Bose, C. Hanson, K. Romero, G. Diette & N.N. Hansel. 2019. Omega-3 and Omega-6 Intake Modifies Asthma Severity and Response to Indoor Air Pollution in Children. American journal of respiratory and critical care medicine, 199(12), 1478-1486. https://doi.org/10.1164/rccm.201808-1474OC
[7] Clark C. C. T., M. Taghizadeh, M. Nahavandi & S. Jafarnejad. 2019. Efficacy of ω-3 supplementation in patients with psoriasis: a meta-analysis of randomized controlled trials. Clinical rheumatology, 38(4), 977-988. https://doi.org/10.1007/s10067-019-04456-x
[8] Delpino F. M., J.M. Figueiredo, B.G.C. da Silva, T.G. da Silva, G.C. Mintem, R.M. Bielemann & D.P. Gigante. 2022. Omega-3 supplementation and diabetes: A systematic review and meta-analysis. Critical reviews in food science and nutrition, 62(16), 4435-4448. https://doi.org/10.1080/10408398.2021.1875977
[9] Deng W., Z. Yi, E. Yin, R. Lu, H. You & X. Yuan. 2023. Effect of omega-3 polyunsaturated fatty acids supplementation for patients with osteoarthritis: a meta-analysis. Journal of orthopaedic surgery and research, 18(1), 381. https://doi.org/10.1186/s13018-023-03855-w
[10] European Food Safety Authority, EFSA (2012). Scientific Opinion on the Tolerable Upper Intake Level of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA).
[11] Gkiouras K., M.G. Grammatikopoulou, I. Myrogiannis, T. Papamitsou, E.I. Rigopoulou, L.I. Sakkas & D.P. Bogdanos. 2024. Efficacy of n-3 fatty acid supplementation on rheumatoid arthritis’ disease activity indicators: asystematic review and meta-analysis of randomized placebo-controlled trials. Critical reviews in food science and nutrition, 64(1), 16-30. https://doi.org/10.1080/10408398.2022.2104210
[12] Heo H., J.H. Bae, A. Amano, T. Park & Y.H. Choi. 2022. Supplemental or dietary intake of omega-3 fatty acids for the treatment of periodontitis: A meta-analysis. Journal of clinical periodontology, 49(4), 362-377. https://doi.org/10.1111/jcpe.13603
[13] Kelaiditis C. F., E.L. Gibson & S.C. Dyall. 2023. Effects of long-chain omega-3 polyunsaturated fatty acids on reducing anxiety and/or depression in adults; A systematic review and meta-analysis of randomised controlled trials. Prostaglandins, leukotrienes, and essential fatty acids, 192, 102572. https://doi.org/10.1016/j.plefa.2023.102572
[14] Luo S., H. Hou, Y. Wang, Y. Li, L. Zhang, H. Zhang, Q. Jin, G. Wu & X. Wang. 2024. Effects of omega-3, omega-6, and total dietary polyunsaturated fatty acid supplementation in patients with atherosclerotic cardiovascular disease: a systematic review and meta-analysis. Food & function, 15(3), 1208-1222. https://doi.org/10.1039/d3fo02522e
[15] Nadjarzadeh A., R. Dehghani Firouzabadi, N. Vaziri, H. Daneshbodi, M.H. Lotfi & H. Mozaffari-Khosravi. 2013. The effect of omega-3 supplementation on androgen profile and menstrual status in women with polycystic ovary syndrome: A randomized clinical trial. Iranian journal of reproductive medicine, 11(8), 665–672.
[16] Naghshi S., D. Aune, J. Beyene, S. Mobarak, M. Asadi & O. Sadeghi. 2021. Dietary intake and biomarkers of alpha linolenic acid and risk of all cause, cardiovascular, and cancer mortality: systematic review and dose-response meta-analysis of cohort studies. BMJ (Clinical research ed.), 375, n2213. https://doi.org/10.1136/bmj.n2213
[17] Natto Z. S., W. Yaghmoor, H.K. Alshaeri & T.E. Van Dyke. 2019. Omega-3 Fatty Acids Effects on Inflammatory Biomarkers and Lipid Profiles among Diabetic and Cardiovascular Disease Patients: A Systematic Review and Meta-Analysis. Scientific reports, 9(1), 18867. https://doi.org/10.1038/ s41598-019-54535-x
[18] Pan A., M. Chen, R. Chowdhury, J.H. Wu, Q. Sun, H. Campos, D. Mozaffarian & F.B. Hu. 2012. α-Linolenic acid and risk of cardiovascular disease: a systematic review and meta-analysis. The American journal of clinical nutrition, 96(6), 1262-1273. https://doi.org/10.3945/ajcn.112.044040
[19] Rezaei S., M.R. Sasani, M. Akhlaghi & A. Kohanmoo. 2020. Flaxseed oil in the context of a weight loss programme ameliorates fatty liver grade in patients with non-alcoholic fatty liver disease: arandomised double-blind controlled trial. The British journal of nutrition, 123(9), 994-1002. https://doi.org/10.1017/ S0007114520000318
[20] Salem N. Jr & M. Eggersdorfer. 2015. Is the world supply of omega-3 fatty acids adequate for optimal human nutrition?. Current opinion in clinical nutrition and metabolic care, 18(2), 147154. https://doi. org/10.1097/MCO.0000000000000145
[21] Stoodley I., M. Garg, H. Scott, L. Macdonald-Wicks, B. Berthon & L. Wood. 2019. Higher Omega-3 Index Is Associated with Better Asthma Control and Lower Medication Dose: A Cross-Sectional Study. Nutrients, 12(1), 74. https://doi.org/10.3390/nu12010074
[22] Takic M., B. Pokimica, G. Petrovic-Oggiano & T. Popovic. 2022. Effects of Dietary α-Linolenic Acid Treatment and the Efficiency of Its Conversion to Eicosapentaenoic and Docosahexaenoic Acids in Obesity and Related Diseases. Molecules (Basel, Switzerland), 27(14), 4471. https://doi.org/10.3390/molecules27144471
[23] Tseng P. T., B.Y. Zeng, J.J. Chen, C.H. Kuo, B.S. Zeng, J.S. Kuo, Y.S. Cheng, C.K. Sun, Y.C. Wu, Y.K. Tu, B. Stubbs, A.F. Carvalho, C.S. Liang, T.Y. Chen, C.W. Hsu, M.W. Suen, C.P. Yang, S.P. Hsu, Y.W. Chen, Y.L. Shiue, … P.Y. Lin. 2024. High Dosage Omega-3 Fatty Acids Outperform Existing Pharmacological Options for Migraine Prophylaxis: A Network Meta-Analysis. Advances in nutrition (Bethesda, Md.), 15(2), 100163. https://doi.org/10.1016/j.advnut.2023.100163
[24] U.S. Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center. FoodData Central.
[Internet].
[cited (enter date)]. Dostęp: https://fdc.nal.usda.gov/.
[25] Vell M. S., K.T. Creasy, E. Scorletti, K.S. Seeling, L. Hehl, M.D. Rendel, K.M. Schneider & C.V. Schneider. 2023. Omega-3 intake is associated with liver disease protection. Frontiers in public health, 11, 1192099. https://doi.org/10.3389/fpubh.2023.1192099
[26] Wang T., X. Zhang, N. Zhou, Y. Shen, B. Li, B.E. Chen & X. Li. 2023. Association Between Omega-3 Fatty Acid Intake and Dyslipidemia: A Continuous Dose-Response Meta-Analysis of Randomized Controlled Trials. Journal of the American Heart Association, 12(11), e029512. https://doi.org/10.1161/ JAHA.123.029512
[27] Wang Y. H., S.Y. Huang, H.P. Kuo, H.Y. Fan, A. Moreira, M.M. Papamichael & Y.C. Chen. 2021. N-3 fatty acid supplementation in asthma management: A systematic review and meta-analysis. Allergy, 76(11), 3042-3046. https://doi.org/10.1111/all.15043
[28] Watson P. D., P.S. Joy, C. Nkonde, S.E. Hessen & D.G. Karalis. 2009. Comparison of bleeding complications with omega-3 fatty acids + aspirin + clopidogrel--versus--aspirin + clopidogrel in patients with cardiovascular disease. The American journal of cardiology, 104(8), 1052-1054. https://doi.org/10.1016/ j.amjcard.2009.05.055
[29] Wu J. H., R. Micha, F. Imamura, A. Pan, M.L. Biggs, O. Ajaz, L. Djousse, F.B. Hu & D. Mozaffarian. 2012. Omega-3 fatty acids and incident type 2 diabetes: a systematic review and meta-analysis. The British journal of nutrition, 107 Suppl 2(0 2), S214-S227. https://doi.org/10.1017/ S0007114512001602
[30] Yan J. H., B.J. Guan, H.Y. Gao & X.E. Peng. 2018. Omega-3 polyunsaturated fatty acid supplementation and non-alcoholic fatty liver disease: Ameta-analysis of randomized controlled trials. Medicine, 97(37), e12271. https://doi.org/10.1097/MD.0000000000012271
[31] Yan J., M. Liu, D. Yang, Y. Zhang & F. An. 2022. Efficacy and Safety of Omega-3 Fatty Acids in the Prevention of Cardiovascular Disease: A Systematic Review and Meta-analysis. Cardiovascular drugs and therapy, 10.1007/s10557-022-07379-z. Advance online publication. https://doi.org/10.1007/ s10557-022-07379-z
[32] Yue H., B. Qiu, M. Jia, W. Liu, X.F. Guo, N. Li, Z.H. Xu, F.L. Du, T. Xu & D. Li. 2021. Effects of α-linolenic acid intake on blood lipid profiles: a systematic review and meta-analysis of randomized controlled trials. Critical reviews in food science and nutrition, 61(17), 2894-2910. https://doi.org/10.1080/10408398. 2020.1790496
[33] Zafari M., F. Behmanesh & A. Agha Mohammadi. 2011. Comparison of the effect of fish oil and ibuprofen on treatment of severe pain in primary dysmenorrhea. Caspian journal of internal medicine, 2(3), 279-282.
[34] Zhang X., J.A. Ritonja, N. Zhou, B.E. Chen & X. Li. 2022. Omega-3 Polyunsaturated Fatty Acids Intake and Blood Pressure: A Dose-Response Meta-Analysis of Randomized Controlled Trials. Journal of the American Heart Association, 11(11), e025071.
[35] Zhou J., W. Zuo, Y. Tan, X. Wang, M. Zhu & H. Zhang. 2023. Effects of n-3 polyunsaturated fatty acid on metabolic status in women with polycystic ovary syndrome: a meta-analysis of randomized controlled trials. Journal of ovarian research, 16(1), 54. https://doi.org/10.1186/s13048-023-01130-4.

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