Czasopismo | INŻYNIERIA MATERIAŁOWA | Rocznik 2010 - zeszyt 3

Development of Ti-based materials for alloplastic implants

nr katalogowy: 52784

The Ti-based biomaterials, light materials of highest corrosion resistance and biocompatibility [1], have also some disadvantages. They may slowly dissolve and result in serious illnesses if the Ti-Al-V alloy is applied [2]. The Ti alloys have Young modulus too high as compared to that of a bone [3], fatigue limit too low [4], and the bone-implant interface strength too weak [5]. The new no Al and no V alloys are developed [6]. This paper is aimed at demonstrating the previous results and current research work in this area made by Advanced Biomaterials Research Group at the Faculty of Mechanical Engineering, GUT. EARLY AND LATE REACTIONS TO METALLIC IMPLANTS The research is made on possible allergies of patients to titanium and Ti alloys. The cases of such allergies were discovered in hospital examinations, mainly for stainless steels but also a case for Ti alloy was found. The biodegradation can result from different origin: presence of bacteria [1÷3], wear of surgical tools, improper material [3, 4]. Even for Ti alloy severe degradation can occur (Fig. 1). The modelisation of change in biological environment of an implant following inflammation process and assessment of metallic ions` release by special tests and sensitive chemical techniques are performed. EFFECTS OF BACTERIA ON CORROSION One of possible determinants of early allergies and inflammation processes can be presence of bacteria [1, 4, 5]. The exposure tests in biological environments have shown that different bacteria may have different and substantial effect on corrosion resistance of titanium alloy. Especially, in presence of Staphylococcus aureus no important corrosion occurs and Enterobacter cloacae presence results in fast corrosion - Figure 2. The results are explained by a model under elaboration in which biofilm of different thickness, permeability and distance from a metal surface affects composition and pH of solution adjacent to a metal, creating c[...]

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2010-3

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